Feed on Posts or Comments 05 September 2008

Pharmaceutical Raw Materials admin on 06 Dec 2007 12:04 am

Aspirin

Aspirin is used for:

Treatment of aches and pains associated with headache, common cold, and sore throat and for reduction of fever. It may be used to reduce the risk of death and lessen the damaging effects of an acute heart attack. It is also used to reduce the risk of heart attacks and strokes in certain men and women who have already had a heart attack or ischemic stroke. It may also be used for other conditions as determined by your doctor.

Aspirin is a nonsteroidal anti-inflammatory drug (NSAID). It works by inhibiting several different chemical processes within the body that cause pain, inflammation, and fever. It also reduces the tendency for blood to clot.

Do NOT use Aspirin if:

  • you are allergic to any ingredient in Aspirin
  • you are a child or teenager with influenza (flu) or chickenpox
  • you have bleeding problems such as hemophilia, von Willebrand disease, or low blood platelets
  • you have active severe bleeding
  • you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness), to aspirin, salicylates (eg, salsalate), tartrazine, or an NSAID (eg, ibuprofen, naproxen, celecoxib)
  • you are taking citrate salts (eg, calcium citrate) or mycophenolate
  • Before Using Aspirin:

    Some medical conditions may interact with Aspirin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, plan to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines or other substances
    • if you have alcoholism or if you consume 3 or more alcohol containing drinks every day
    • if you have asthma, bleeding or clotting problems, growths in the nose (nasal polyps), hives, kidney or liver problems, heart problems, high blood pressure, stomach or intestinal problems (eg, ulcer, inflammation), heartburn, upset stomach, stomach pain, the flu, chickenpox, or vitamin K deficiency
    • if you have high levels of calcium, aluminum, or magnesium in your blood
    • if you are a child with a stroke, a weakened blood vessel (cerebral aneurysm) or bleeding in the brain, arthritis (rheumatic disease), or Kawasaki syndrome (a rare inflammation causing heart problems in children)
    • if you have had your tonsils out or you have had oral (eg, mouth) surgery within the past 7 days

    Some MEDICINES MAY INTERACT with Aspirin . Tell your health care provider if you are taking any other medicines, especially any of the following:

    • Carbonic anhydrase inhibitors (eg, acetazolamide) because they may decrease Aspirin ’s effectiveness
    • Anticoagulants (eg, heparin, warfarin), clopidogrel, dicumarol, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, celecoxib) because the risk of their side effects, including risk of bleeding, may be increased by Aspirin
    • Insulin and oral antidiabetics (eg, glyburide, nateglinide) because the risk of their side effects, including low blood sugar (eg, hunger, shakiness or weakness, dizziness, headache, sweating), may be increased by Aspirin
    • Citrate salts (eg, calcium citrate) because the risk of toxicity may be increased
    • Methotrexate or valproic acid because the risk of their actions and side effects may be increased by Aspirin
    • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), diuretics (eg, furosemide), mycophenolate, penicillamine, probenecid, sulfinpyrazone, or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Aspirin

    This may not be a complete list of all interactions that may occur. Ask your health care provider if Aspirin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

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